产品货号:
Z37151
中文名称:
FMO3抗体
英文名称:
Anti-FMO3 Antibody (Clone#OTI3H1)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-FMO3 Antibody (Clone#OTI3H1) |
指标别名 | Dimethylaniline oxidase 3;FMO 3;FMO form 2;FMO II;FMO3;FMOII;TMAU |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC |
基因名称 | FMO3 |
克隆号 | OTI3H1 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Human recombinant protein fragment corresponding to amino acids 1-291 of human FMO3(NP_008825) produced in E.coli. |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | FMO3(Flavin-containing Monooxygenase 3) is an enzyme that in humans is encoded by the FMO3 gene.The mammalian flavin-containing monooxygenases(FMO) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues.The FMO3 gene contains 1 noncoding and 8 coding exons.The FMO3 gene is mapped on 1q24.3.Using quantitative RNase protection assays,FMO3 is present in low abundance in fetal liver and lung and in adult kidney and lung,and in much greater abundance in adult liver.By Western blot analysis of human liver microsomal samples ranging from 8 weeks gestation to 18 years of age,FMO1 is the major fetal isoform and FMO3 is the major adult isoform.FMO3 was expressed at intermediate levels until 11 years of age when a gender-independent increase in FMO3 expression was observed during puberty.Sufferers of trimethylaminuria may display a reduced ability to metabolize substrates for FMO3 such as nicotine.FMO3 metabolizes a number of drugs,including amphetamine,clozapine,deprenyl,metamphetamine,tamoxifen,ethionamide,thiacetazone,and sulindac sulfide. |
Uniprot ID | P31513 |
基因名全称 | flavin containing monooxygenase 3 |
蛋白名全称 | Dimethylaniline monooxygenase [N-oxide-forming] 3 |
推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 |
相关搜索:FMO3抗体,FMO3单抗,Anti-FMO3 Antibody (Clone#OTI3H1)